For starters, there are several modern loads that have been specifically created for use as self defense shells from short barrel handguns. Ever since the Judge/Governor gained in popularity. Secondly, you have folks like me that love to bank fish in areas rife with cottonmouths, copperhead, etc. A pocket size pistol that is easy to carry fits the bill in that situation. And will also chamber the 45 if you want more stopping power...